Molecular cloning and sequence analysis of a mouse Y chromosome RNA transcript expressed in the testis.
نویسندگان
چکیده
Using a Y specific probe (pY353/B) taken from a flow sorted mouse Y chromosome library we have identified a family of RNA transcripts encoded by the Y chromosome. These transcripts which are approximately 1.3 Kb in length are present in testis PolyA+ RNA but can not be detected in either male liver, spleen, kidney, brain, heart or lung tissues. Isolation and sequence analysis of a corresponding cDNA shows it to contain a potential coding sequence of 696bp. These data show that the Y chromosome is transcriptionally active in the adult mouse testis.
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عنوان ژورنال:
- Nucleic acids research
دوره 15 7 شماره
صفحات -
تاریخ انتشار 1987